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[39] Biological importance [edit] Cysteine and cystine [edit] As the functional group of the proteinogenic amino acid cysteine, the thiol group plays a very important role in biology

Notably, while classical organoid systems have long been established exclusively from crypt-resident stem cells 27,28 , our findings challenge this longstanding paradigm by demonstrating that mutation-free villus-derived cells can indeed establish organoids via fetal reversion, revealing remarkable regenerative flexibility of the adult intestinal epithelium

Oral administration has the benefit of high patient compliance and has demonstrated the potential to target brain iron pathology, especially with BBB-permeant agents like DFP

doi: 10.1136/hrt.75.6.573 56 ObreE.RossignolR

Nevertheless, the rationale for PB-TURSO in the treatment of ALS remains to be clarified, as the transcriptional and metabolic effects of the combination differ significantly from those of PB or Turso alone